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Edgar Jost Selected Research

Acute Myelomonocytic Leukemia

12/2015The Fc-alpha receptor is a new target antigen for immunotherapy of myeloid leukemia.
9/2014Targeted ex vivo reduction of CD64-positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B-based cytolytic fusion proteins.

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Edgar Jost Research Topics

Disease

19Neoplasms (Cancer)
08/2021 - 04/2007
13Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021 - 12/2003
4Lymphoma (Lymphomas)
12/2017 - 11/2008
4Leukemia
10/2016 - 01/2004
3Graft vs Host Disease (Graft-Versus-Host Disease)
12/2021 - 11/2015
3Hodgkin Disease (Hodgkin's Disease)
12/2017 - 06/2009
3Hematologic Neoplasms (Hematological Malignancy)
12/2015 - 01/2010
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2015 - 04/2011
2Primary Myelofibrosis (Myelosclerosis)
11/2020 - 12/2014
2Infections
11/2020 - 01/2010
2Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
12/2017 - 12/2007
2Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
12/2017 - 12/2007
2Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
10/2016 - 09/2014
2Breast Neoplasms (Breast Cancer)
10/2016 - 11/2008
2Myeloid Leukemia (Leukemia, Myelocytic)
10/2016 - 12/2015
2Acute Myelomonocytic Leukemia
12/2015 - 09/2014
2Neoplasm Metastasis (Metastasis)
06/2014 - 07/2009
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2009 - 12/2008
2Splenomegaly
11/2008 - 12/2007
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2007 - 01/2004
1Anemia
03/2022
1Malnutrition (Nutritional Deficiencies)
12/2021
1Acute Promyelocytic Leukemia
12/2021
1Pure Red-Cell Aplasia
09/2021
1Werner Syndrome (Werner's Syndrome)
01/2021
1COVID-19
11/2020
1Cytokine Release Syndrome
11/2020
1Pneumonia (Pneumonitis)
11/2020
1Coronavirus Infections
11/2020
1Fibrosis (Cirrhosis)
08/2020
1Hematologic Diseases (Blood Diseases)
01/2019
1Obesity
07/2016
1Overweight
07/2016
1Brain Edema (Cerebral Edema)
07/2014
1Mastitis
07/2014
1Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
07/2014
1Sepsis (Septicemia)
07/2014
1Prostatic Neoplasms (Prostate Cancer)
10/2011
1Plasma Cell Leukemia
08/2011
1Multiple Myeloma
08/2011
1Carcinogenesis
08/2011

Drug/Important Bio-Agent (IBA)

4Proteins (Proteins, Gene)FDA Link
10/2016 - 11/2008
3Granzymes (Granzyme)IBA
09/2014 - 09/2008
3Immunotoxins (Immunotoxin)IBA
09/2011 - 12/2003
2Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2021 - 01/2020
2venetoclaxIBA
08/2021 - 04/2021
2DecitabineFDA Link
01/2021 - 01/2020
2Phosphotransferases (Kinase)IBA
11/2020 - 06/2009
2CytokinesIBA
08/2020 - 08/2011
2DNA (Deoxyribonucleic Acid)IBA
01/2020 - 08/2011
2IgG Receptors (Fc gamma RI)IBA
10/2016 - 12/2015
2AntigensIBA
10/2016 - 12/2015
2Biomarkers (Surrogate Marker)IBA
01/2015 - 06/2014
2Histones (Histone)IBA
08/2011 - 04/2007
2PlatinumIBA
10/2009 - 12/2008
2Messenger RNA (mRNA)IBA
11/2008 - 12/2007
2Rituximab (Mabthera)FDA Link
11/2008 - 12/2007
2Immunoglobulin G (IgG)IBA
09/2008 - 12/2003
1Nonsense Codon (Nonsense Mutation)IBA
03/2022
1VitaminsIBA
12/2021
1Trace Elements (Biometals)IBA
12/2021
1Arsenic Trioxide (Trisenox)FDA Link
12/2021
1ruxolitinibIBA
11/2020
1Janus Kinase InhibitorsIBA
11/2020
1Valproic Acid (Depakote)FDA LinkGeneric
01/2020
1RetinoidsIBA
01/2020
1Histone Deacetylase InhibitorsIBA
01/2020
1Excipients (Suspending Agents)IBA
10/2016
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
10/2016
1Fc(alpha) receptorIBA
12/2015
1angiogeninIBA
12/2015
1MicroRNAs (MicroRNA)IBA
12/2015
1Complement C1 (Complement 1)IBA
01/2015
1Reticulin (Reticular Fiber)IBA
12/2014
1Fibronectins (Fibronectin)IBA
12/2014
1Serine Proteases (Serine Protease)IBA
09/2014
1Anti-Bacterial Agents (Antibiotics)IBA
07/2014
1Adrenal Cortex Hormones (Corticosteroids)IBA
12/2013
1Peptide Hydrolases (Proteases)FDA Link
12/2013
1SerpinsIBA
12/2013
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2012
1Secreted Frizzled-Related ProteinsIBA
08/2012
1UbiquitinIBA
10/2011
1HydrolasesIBA
10/2011
1Surface Antigens (Surface Antigen)IBA
09/2011
1Interleukin-6 (Interleukin 6)IBA
08/2011
1CreatinineIBA
08/2011
1Amino AcidsFDA Link
08/2011

Therapy/Procedure

13Therapeutics
12/2021 - 04/2007
10Drug Therapy (Chemotherapy)
12/2015 - 12/2007
6Cell Transplantation
12/2021 - 12/2017
5Bone Marrow Transplantation (Transplantation, Bone Marrow)
12/2021 - 12/2017
4Immunotherapy
12/2015 - 12/2003
3Hematopoietic Stem Cell Transplantation
08/2021 - 11/2015
2Stem Cell Transplantation
01/2021 - 08/2020
1Erythrocyte Transfusion
09/2021
1Artificial Respiration (Mechanical Ventilation)
11/2020
1Critical Care (Surgical Intensive Care)
11/2020
1Cesarean Section (Caesarean Section)
07/2014
1Radiotherapy
12/2013